Our Research Results

Since we first began more than 40 years ago, Breast Cancer Trials (BCT) has contributed to more than 1,200 peer-reviewed publications and many of these research results have changed practice in the treatment and prevention of breast cancer.

The publication of the results of clinical trials research in a scientific journal or a periodic publication:

  • Fulfils the researchers’ ethical obligations to research participants and the general community;
  • Contributes to medical knowledge so doctors can make scientifically valid assessments of the benefits and risks of a new medicine or treatment for their patients.

BCT publishes study results in accordance with the BCT Publication Policy.

The citations for all of these publications are listed below, ordered by year. To search for a citation, enter a keyword/s and click search. Enclose multiple words in quotes “” to search for an exact match. Alternatively, you can search for clinical trials in a given year or for a particular clinical trial name. 

The majority of the publications can be accessed via PubMed, other research databases or publication storage systems at a university library (if you are a student/member), or directly to the journal or publication online. Many scientific journals provide articles as “open access”; however some require a subscription.



Genomic charicterisation of hormone receptor-positive breast cancer arising in young women.

Luen SJ, Viale G, Nik-Zainal S, Savas P, Kammler R, Dell’Orto P, Biasi O, Degasperi A, Brown LC, Lang I, MacGrogan G, Tondini C, Bellet M, Villa F, Bernardo A, Ciruelos E, Karlsson P, Neven P, Climent M, Muller B, Joshum W, Bonnefoi H, Martino S, Davidson NE, Geyer CE Jr, Walley BA, Ingle JN, Coleman R, Solbach C, Thurlimann B, Colleoni M, Coates AS, Goldhirsch A, Fleming GF, Francis PA, Speed TP, Regan MM, Loi S. Annals of Oncology. 2023; epub 25 January 2023, doi: 10.1016/j.annonc.2023.01.009;, E-pub


Adjuvant exemestane with ovarian suppression in premenopausal breast cancer: long-term follow-up of the combined TEXT and SOFT trials.

Pagani* O, Walley* BA, Francis GF, Colleoni M, Láng I, Gomez Hl, Tondini C, Burstein HJ, Goetz MP, Ciruelos EM, Stearns V, Bonnefoi HR, Martino S, Geyer CE Jr, Chini C, Puglisi F, Spazzapan S, Ruhstaller T, Winder EP, Ruepp B, Loi S, Coates AS, Gelber RD, Goldhirsch A, Regan** MM, Francis** PA, for the SOFT and TEXT Investigators and the International Breast Cancer Study Group. *Co-lead authors. **Co-last authors. Journal of Clinical Oncology. 2022; Epub 15 December 2022. doi: 10.1200/JCO.22.01064, E-pub

Adjuvant endocrine therapy in premenopausal breast cancer: 12-year results from SOFT.

Francis* PA, Fleming* GF, Láng I, Ciruelos EM, Bonnefoi HR, Bellet M, Bernardo A, Climent MA, Martino S, Bermejo B, Burstein HJ, Davidson NE, Geyer CE Jr, Walley BA, Ingle, JN, Coleman RE, Müller B, Le Du F, Loibl S, Winer EP, Ruepp B, Loi S, Colleoni M, Coates AS, Gelber RD, Goldhirsch A, Regan MM, for the SOFT Investigators and the International Breast Cancer Study Group. *Co-lead authors. Journal of Clinical Oncology. 2022; Epub 9 December 2022. doi: 10.1200/JCO.22.01065., E-pub

Back to the Beginning: The role of ovarian suppression in management of hormone sensitive breast cancer in premenopausal women.

Connolly RM, Miller RD. Journal of Clinical Oncology. 2022; epub 15 December 2022 doi: 10.1200/JCO.22.02319., Editorial

Development and Validation of a Composite Biomarker Predictive of Palbociclib + Endocrine Treatment Benefit in Early Breast Cancer: PENELOPE-B and PALLAS Trials.

Loibl S, Denkert C, Liu Y, Knudsen ES, DeMichele A, Zhang Z, Teply-Szymanski J, Filipits M, Fasching PA, Gnant M, Deng S, Balic M, Rojo M, Watson M, Deshpande C, Turner N, Metzger O, Theall KP, Witkiewicz A, Valota O, Symmans WF, Mayer EL. San Antonio Breast Cancer Symposium. 2022; Abstract #PD17-05, Abstract

Immunohistochemical markers and determinants of clinical response in the Penelope-B trial.

Knudsen ES, Rachakonda S, Marme F, Marin M, Untch M, Bonnefoi HR, Schmitt WD, Sung-Bai K, Bear HD, Witkiewicz A, Seock-Ah I, DeMichele A, Van’t Veer L, McCarthy N, Sinn BV, Gelmon K, Garcia-Saenz JA, Kelly CM, Reimer T, Turner N, Rojo F, Filipits M, Fasching PA, Schem C, Martin L-A, Liu Y, Toi M, Rugo H, Gnant M, Makris A, Furlanetto J, Weber K, Denkert C, Loibl S. San Antonio Breast Cancer Symposium. 2022; Abstract #PD17-06, Abstract

Total Publications: 1273