Our Research Results

Since we first began more than 40 years ago, Breast Cancer Trials (BCT) has contributed to more than 1,200 peer-reviewed publications and many of these research results have changed practice in the treatment and prevention of breast cancer.

The publication of the results of clinical trials research in a scientific journal or a periodic publication:

  • Fulfils the researchers’ ethical obligations to research participants and the general community;
  • Contributes to medical knowledge so doctors can make scientifically valid assessments of the benefits and risks of a new medicine or treatment for their patients.

BCT publishes study results in accordance with the BCT Publication Policy.

The citations for all of these publications are listed below, ordered by year. To search for a citation, enter a keyword/s and click search. Enclose multiple words in quotes “” to search for an exact match. Alternatively, you can search for clinical trials in a given year or for a particular clinical trial name. 

The majority of the publications can be accessed via PubMed, other research databases or publication storage systems at a university library (if you are a student/member), or directly to the journal or publication online. Many scientific journals provide articles as “open access”; however some require a subscription.

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PUBLICATIONS

2025

Quality-of-life and symptom severity in the PALLAS randomized trial of palbociclib with adjuvant endocrine therapy in early breast cancer (AFT-05, ABCSG-42, BIG-14-03, PrE0109).

Naughton MJ, Zahrieh DM, Gnant M, Zdenkowski N, Lemieux J, Mao JJ, Bjelic-Radisic V, Shinn E, Balic M, Thomssen C, Meisel JL, Ruiz GM, Loibl S, Isaacs C, Cameron D, Henao-Carrasco FM, Goetz MP, Singer SF, Werutsky G, Rugo HS, Vetter M, Tseng L-M, Miller K, Fitzal F, Gil Gil JM, Park H, Linderholm B, Bajetta E, Dayao Z, Prat A, Ehrhardt K, Metzger O, Arahmani A, Law EH, Partridge AH, Carey LA, Zoroufy A, Dueck AC, O’Brien P, Hlauschek D, DeMichele A & Mayer EL. ESMO Open. 2025; 10(6):105120, DOI: 10.1016/j.esmoop.2025.105120, E-pub

Radiation omission in patients with clinically node-negative breast cancer undergoing lumpectomy (ROSALIE).

Parvez E, Basik M, Parpia S, Levine MN, Whelan TJ, Muanza T. Journal of Clinical Oncology. 2025; 43(suppl 16):Abstract TPS628., Abstract

A double-blind placebo controlled randomized phase III trial of fulvestrant and ipatasertib as treatment for advanced HER2-negative and estrogen receptor positive (ER+) breast cancer following progression on first line CDK 4/6 inhibitor and aromatase inhibitor: The CCTG/BCT MA.40/FINER study (NCT04650581).

Chia SKL, Redfern AD, Ayoub J-BM, Chalchal HI, Rayson D, Rushton M, Desbiens C, Sabanathan D, Raphael J, Chan A, Singh J, Simmons CE, Zdenkowski N, Wilson S, Rodin D, Cescon DW, Schimmoller F, Gallinaro L, Chen BE, Paralekar WR. Journal of Clinical Oncology. 2025; 43(suppl 17).:Abstract LBA1005., Presentation

Drug-drug interactions between palbociclib and proton pump inhibitors in early breast cancer: an exploratory analysis of PALLAS (ABCSG-42/AFT-05/BIG-14-13/PrE0109).

Agostinetto E, Pfeiler G, Hlauschek D, Mayer EL, Lambertini M, de Azambuja E, Bellet-Ezquerra M, Meisel JL, Rubovszky G, Zdenkowski N, Novik Y, Ruiz-Borrego M, Gelmon KA, Mamounas EP, Iwata H, Lu DR, Soelkner L, Fesl C, Gnant M, DeMichele A. ESMO Open. 2025; 10(1):104096, DOI: 10.1016/j.esmoop.2024.104096., E-pub

Reexamining the long-term treatment outcomes in hormone sensitive breast cancer.

Halfter K, Schlesinger-Raab A, Holzel D. ESMO Open. 2025; 10(4 suppl).:DOI: https://doi.org/10.1016/j.esmoop.2025.104810, Abstract 256P., Abstract

Adjuvant pertuzumab or placebo + trastuzumab + chemotherapy (P or Pla + T + CT) in patients (pts) with early HER2-positive operable breast cancer in APHINITY: Final analysis at 11.3 years’ median follow-up.

Loibl S, Piccart M, Clark E, Viale G, Caballero C, Henry C, Tomasello G, Fein LE, Gnant MI, Kuemmel S, Plummer C, Im S-A, Yang Y-S, Takano T, De la Haba Rodriguez J, McConnel R, De Azambuja E, Procter M, Bines J, Gelber RD. ESMO Open. 2025; 10(suppl 4):DOI: https://doi.org/10.1016/j.esmoop.2025.105112, Abstract LBA1, Presentation

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Total Publications: 1349