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ATAC

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ANZ 9801: ATAC

BCT Study Chair:

Prue Francis

A randomised double-blind trial comparing Arimidex alone with Nolvadex alone with Arimidex and Nolvadex in combination, as adjuvant treatment in postmenopausal women with breast cancer.

international

9192

INTERNATIONAL

Total number of trial

participants internationally

australia & new zealand

174

AUSTRALIA & NEW ZEALAND

Total number of trial participants

in Australia and New Zealand

institutions

11

INSTITUTIONS

Total number of participating institutions

in Australia and New Zealand

ATAC PUBLICATIONS

2024

Reductions in recurrence in women with early breast cancer entering clinical trials between 1990 and 2009: a pooled analysis of 155 746 women in 151 trials.

Early Breast Cancer Trialists’ Collaborative Group. The Lancet. 2024; 4041407-18, epub 12 October 2024, E-pub

2018

Importance of adverse events during endocrine treatment for the prediction of late distant recurrences.

Sestak I, Dowsett M, Cuzick J. SABCS 2018; P4-08-02, Poster

2017

Integration of clinical variables for the prediction of late distant recurrence in patients with oestrogen receptor positive breast cancer treated with 5 years of endocrine therapy.

Sestak I, Regan M, Dodson A, Viale G, Thürlimann B, Colleoni M, Cuzick J, Dowsett M. SABCS 2017; GS6-01 (oral presentation), Presentation

HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2.

Bartlett JMS, Ahmed I, Regan MM, Sestak I, Mallon EA, Dell’Orto P, Thurlimann B, Seynaeve C, Putter H, Van de Velde CJH, Brookes CL, Forbes JF, Viale G, Cuzick J, Dowsett M, Rea DW, on behalf of the Translational Aromatase Inhibitor Overview Group (Trans-AIOG). European Journal of Cancer. 2017; 79129-138 (epub 9 May 2017), doi.org/10.1016/j.ejca.2017.03.033, E-pub

2016

Long-term comparison of anastrozole versus tamoxifen: Results from LATTE/ATAC.

Cuzick J, Sestak I, Bianco A, Strobbe L, Bergh J, Hanusch C, Neven P, Dowsett M, Forbes JF, Buzdar A, Smith R, Howell A. SABCS 2016. 2016; P2-09-03, Poster

Comprehensive comparison of prognostic signatures for breast cancer in TransATAC.

Sestak I, Buus R, Cuzick J, Dubsky P, Kronenwett R, Ferree S, Sgroi D, Schnabel C, Baehner R, Mallon E, Dowsett M. SABCS 2016. 2016; S6-05, Abstract

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Institutions