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IES

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BIG 2-97/IBCSG 16-98: IES

BCT Study Chair:

Alan Coates

Randomised double blind trial in postmenopausal women with primary breast cancer who have received adjuvant tamoxifen for 2-3 years, comparing subsequent adjuvant exemestane treatment with further tamoxifen.

international

4673

INTERNATIONAL

Total number of trial

participants internationally

australia & new zealand

70

AUSTRALIA & NEW ZEALAND

Total number of trial participants

in Australia and New Zealand

institutions

10

INSTITUTIONS

Total number of participating institutions

in Australia and New Zealand

IES PUBLICATIONS

2017

Long-term follow-up of the intergroup exemestane study.

Morden JP, Alvarez I, Bertelli G, Coates AS, Coleman R, Fallowfield L, Jassem J, Jones S, Kilburn L, Lønning PE, Ortmann O, Snowdon C, van de Velde C, Andersen J, Del Mastro L, Dodwell D, Holmberg S, Nicholas H, Paridaens R, Bliss JM, Coombes RC. Journal of Clinical Oncology. 2017; 35(22):2507-2514 (epub 3rd May 2017), Journal

2014

Patient-level meta-analysis of randomized trials of aromatase inhibitors (AI) versus tamoxifen (Tam)

Forbes JF, Dowsett M, Bradley R, Ingle JN, Aihara T, Bliss JM, Boccardo FM, Coates AS, Coombes RC, Cuzick JM, Dubsky PC, Gnant M, Kaufmann M, Kilburn LS, Perrone F, Rea D, Thurlimann BJK, Van De Velde CJH, Davies C, Gray RG, on behalf of EBCTCG’s AIOG J Clin Oncol 2014; 32:5s(suppl; abstr 529), Poster

2012

Carpal tunnel syndrome and musculoskeletal symptoms in postmenopausal women with early breast cancer treated with exemestane or tamoxifen after 2-3 years of tamoxifen: A retrospective analysis of the Intergroup Exemestane Study.

Mieog JSD, Morden JP, Bliss JM, Coombes RC, van de Velde CJH , on behalf of the IES Steering Committee. Lancet Oncol. 2012; 19 JanuaryE-Pub, Journal

Disease-related outcomes with long-term follow-up: An updated analysis of the Intergroup Exemestane Sudy.

Bliss JM, Kilburn LS, Coleman RE, Forbes JF, Coates AS, Jones SE, Jassem J, Delozier T, Andersen J, Paridaens R, van de Velde CJH, Lønning PE, Morden J, Reise J, Cisar L, Menschik T, Coombes RC. J Clin Oncol. 2012; 30(7):709-717, Journal

2010

Reversal of skeletal effects of endocrine treatments in the Intergroup Exemestane Study.

Coleman RE, Banks LM, Girgis SI, Vrdoljak E, Fox J, Cawthorn SJ, Patel A, Bliss JM, Coombes RC, Kilburn LS. Breast Cancer Res Treat 2010; 124(1):153-161, Journal

2009

Disease related outcome with long term follow-up: An updated analysis of the Intergroup Exemestane Study (IES).

Bliss JM, Kilburn LS, Coleman RE, Forbes JF, Coates AS, Jones SE, Jassem J, Delozier T, Andersen J, Paridaens RJ, Coombes RC, on behalf of the IES Steering Committee. SABCS 2009; 12, Abstract

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